Indole-3-carboxamides as glucokinase (gk) activators

Details Indole-3-carboxamides as glucokinase (gk) activators Indole-3-carboxamides as glucokinase (gk) activators

C - Chemistry, Metallurgy

07

D

C07D 403/12 (2006.01) A61K 31/427 (2006.01) A61P 3/10 (2006.01) C07D 401/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2499329

The present invention provides glucokinase activators of formula (I), wherein R1, R2 and R3 are defined in the specification. Glucokinase activators are useful for increasing insulin secretion in the treatment of type II diabetes.

L'invention concerne des activateurs de glucokinase de formule (I). Dans cette formule, R?1¿, R?2¿ et R?3¿ sont définis dans la description. Des activateurs de glucokinase sont utiles pour augmenter la sécrétion d'insuline dans le traitement de diabètes de type II.

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