Cyclic compound and salt thereof

Details Cyclic compound and salt thereof Cyclic compound and salt thereof

C - Chemistry, Metallurgy

07

K

C07K 7/64 (2006.01) A61K 36/06 (2006.01) A61K 38/00 (2006.01) A61P 31/10 (2006.01) C12N 1/14 (2006.01) C12P 21/02 (2006.01)

Patent

CA 2718395

A compound useful as an antifungal agent, particularly a therapeutic agent for deep-seated mycoses, is provided. A fungus Acremonium persicinum was collected, and cyclic compounds were isolated from culture liquids thereof. The present inventors confirmed that the cyclic compounds or salts thereof have a potent antifungal activity and are useful as medicaments, particularly an antifungal agent, and thus the present invention was completed. The cyclic compound and the salt thereof according to the present invention can be used as an agent for preventing or treating mycoses, particularly deep-seated mycoses.

L'invention concerne un composé qui est utile comme agent antifongique, en particulier, un agent thérapeutique pour des mycoses profondes. Un champignon Acremonium persicinum est recueilli et un composé cyclique est isolé d'une culture du champignon. Il est confirmé que le composé cyclique ou un sel de celui-ci possède une bonne activité antifongique et est par conséquent utile comme agent médicinal, en particulier comme agent antifongique. Le composé cyclique ou un sel de celui-ci peut être utilisé comme agent prophylactique ou thérapeutique pour des mycoses, en particulier des mycoses profondes.

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