Differential patterns of gene expression that predict for...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01)

Patent

CA 2486105

The invention pertains to differential gene expression profiles for docetaxel responsiveness. The invention identifies molecular profiles in primary breast cancers that appear to predict response or lack of response to docetaxel. This invention provides methods involving prediction of docetaxel responsiveness as well as arrays for use in determining docetaxel responsiveness.

La présente invention a trait à des profils différentiels d'expression génétiques permettant la détermination de la sensibilité au docetaxel. L'invention identifie des profils moléculaires dans des cancers primitifs du sein qui semblent prédire une sensibilité ou une insensibilité au docetaxel. La présente invention a également trait à des procédés permettant la prédiction de la sensibilité au docetaxel ainsi que des jeux ordonnés d'échantillons utiles dans la détermination de la sensibilité au docetaxel.

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