A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/56 (2006.01) A61K 31/07 (2006.01) A61K 31/724 (2006.01) A61P 17/00 (2006.01)
Patent
CA 2664083
The present invention is related to a pharmaceutical combination of a glucocorticoid and a .beta.-cyclodextrin conjugated vitamin A derivative complex as well as a pharmaceutical composition comprising the same. The combination and the composition of the invention can be used for reducing or eliminating skin atrophy induced by treatment with glucocorticoids (GC). Also comprised is a method for reducing or eliminating skin atrophy induced by GC treatment. Furthermore the invention concerns a kit comprising a glucocorticoid and a .beta.-cyclodextrin conjugated vitamin A derivative complex.
L'invention concerne une combinaison pharmaceutique d'un glucocorticoïde et d'un complexe de dérivés de vitamine A conjugués à .beta.-cyclodextrine, ainsi qu'une composition pharmaceutique contenant cette combinaison. La combinaison et la composition selon l'invention peuvent être utilisées dans la réduction ou l'élimination de l'atrophie cutanée induite par un traitement aux glucocorticoïdes (GC). L'invention concerne également une méthode de réduction ou d'élimination de l'atrophie cutanée induite par un traitement aux GC. L'invention concerne enfin un kit contenant un glucocorticoïde et un complexe de dérivés de vitamine A conjugués à .beta.-cyclodextrine.
Thom Erling
Wadstein Jan
Kirby Eades Gale Baker
Pharma Medico Research Limited
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