C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 229/14 (2006.01) A61K 31/195 (2006.01) A61K 31/33 (2006.01) C07D 213/62 (2006.01) C07D 213/63 (2006.01) C07D 213/643 (2006.01) C07D 213/65 (2006.01) C07D 307/79 (2006.01) C07D 307/83 (2006.01) C07D 317/64 (2006.01) C07D 319/18 (2006.01) C07D 333/64 (2006.01)
Patent
CA 2451673
This invention relates to a series of substituted aromatic ethers of the formula (I), wherein ring A and X and Y are defined as in the specification, that exhibit activity as glycine transport inhibitors, their pharmaceutically acceptable salts, pharmaceutical compositions containing them, and their use for the enhancement of cognition and the treatment of the positive and negative symptoms of schizophrenia and other psychoses in mammals, including humans.
L'invention concerne une série d'éthers aromatiques substitués de formule (I), dans laquelle les cycles A, X et Y sont tels que définis dans la description, montrant une activité d'inhibiteurs de transport de la glycine, leurs sels, acceptables sur le plan pharmaceutique, des compositions pharmaceutiques les contenant, et leurs utilisations pour l'amélioration de la connaissance du traitement des symptômes positifs et négatifs de la schizophrénie et d'autres psychoses chez les mammifères, y compris chez l'homme.
Pfizer Products Inc.
Sim & Mcburney
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