Thymidylate synthase haplotype is associated with tumor...

Details Thymidylate synthase haplotype is associated with tumor... Thymidylate synthase haplotype is associated with tumor...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01)

Patent

CA 2727247

The invention provides compositions and methods for determining the likelihood of tumor recurrence following treatment with 5-FU based adjuvant therapy for Stage II or Stage III colon cancer patients. After determining if a patient is less likely to experience tumor recurrence once treated, the invention also provides methods for treating these patients.

L'invention concerne des compositions et des procédés pour déterminer la probabilité de récurrence tumorale après traitement par une thérapie d'appoint à base de 5-FU pour des patients atteints d'un cancer du côlon au stade II ou au stade III. Après avoir déterminé si un patient est moins susceptible de subir une récurrence tumorale une fois qu'il a été traité, l'invention propose également des procédés de traitement de ces patients.

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