C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 317/50 (2006.01) A61K 31/165 (2006.01) A61K 31/35 (2006.01) C07C 313/04 (2006.01) C07C 317/40 (2006.01) C07C 323/41 (2006.01) C07D 311/58 (2006.01) C07D 311/76 (2006.01)
Patent
CA 2048325
ABSTRACT ACETAMIDE DERIVATIVES The invention concerns novel N-phenylacetyl and related acyl derivatives of (4-amino-2,6-dimethylphenylsulphonyl)nitromethane and pharmaceutically acceptable salts thereof which are inhibitors of the enzyme aldose reductase and are of value, for example, in the treatment of certain peripheral effects of diabetes and galactosemia. Also disclosed are pharmaceutical compositions containing one of the derivatives and processes for the manufacture and use of the derivatives.
Brittain David Robert
Brown Steven Paul
Cooper Anthony Loren
Longridge Jethro Lawrence
Morris Jeffrey James
Riches Mckenzie & Herbert Llp
Zeneca Limited
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