C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 225/02 (2006.01) A61K 31/427 (2006.01) A61P 35/00 (2006.01) C07D 315/00 (2006.01) C07D 417/06 (2006.01)
Patent
CA 2401800
The present invention provides convergent processes for preparing epothilones, desoxyepothilones, and analogues thereof. The present invention further provides novel compositions and methods for the treatment of cancer and additionally provides methods for the treatment of cancer which has developed a multi-drug phenotype.
La présente invention concerne des procédés convergents permettant de préparer des épothilones, des désoxyépothilones et leurs analogues. La présente invention concerne également de nouvelles compositions et de nouveaux procédés pour le traitement du cancer, ainsi que des procédés pour le traitement de cancers développant un phénotype de multirésistance médicamenteuse.
Chappell Mark
Chou Ting-Chao
Danishefsky Samuel J.
Lee Chul Bom
Stachel Shawn
Robic
Sloan-Kettering Institute For Cancer Research
The Trustees Of Columbia University In The City Of New York
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