Novel embolizing compositions

Details Novel embolizing compositions Novel embolizing compositions

A - Human Necessities

61

K

A61K 47/30 (2006.01) A61K 47/48 (2006.01) A61K 49/00 (2006.01) A61K 49/04 (2006.01) A61L 24/00 (2006.01) A61L 24/04 (2006.01) A61L 24/06 (2006.01) A61L 24/08 (2006.01)

Patent

CA 2215356

Disclosed are novel compositions for embolizing blood vessels which are particularly suited for treating vascular lesions via catheter delivery. In one embodiment, the compositions of this invention comprise a biocompatible polymer, a biocompatible solvent and a biocompatible water insoluble contrast agent characterized by having an average particle size of less than about 10 µm. In another embodiment, the biocompatible polymer in these compositions is replaced with a biocompatible prepolymer.

L'invention porte sur de nouvelles compositions d'embolisation de vaisseaux sanguins spécialement adaptées au traitement des lésions vasculaires par des dépôts effectués par cathéter. Dans l'une de leurs variantes, les compositions comportent un polymère biocompatible, un solvant biocompatible et un agent de contraste biocompatible non hydrosoluble présentant une taille de particules moyenne inférieure à environ 10 mu m. Dans une autre variante, ce polymère biocompatible est remplacé par un prépolymère biocompatible.

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