Medicament coated refractive anterior chamber ocular implant

Details Medicament coated refractive anterior chamber ocular implant Medicament coated refractive anterior chamber ocular implant

A - Human Necessities

61

L

A61L 27/00 (2006.01) A61F 2/16 (2006.01) A61L 27/34 (2006.01) A61L 33/00 (2006.01)

Patent

CA 2115651

A minus power anterior chamber ocular implant for placement in the anterior chamber of a phakic eye having an anatomic lens in situ comprises a negative artificial refracting lens having at least one concave surface, a surface coating which comprises a compatible sulfated polysaccharide medicament coating, such as heparin, and means for positioning the artificial lens in the an- terior chamber of the eye to prevent contact between the implant and the anatomic lens. The implant compensates for refractive errors or creates a specific refraction to assist in visual function and has increased biocompatibility in the anterior chamber of the eye, thereby preventing or mitigating detrimental effects typically associated with the implantation of an uncoated refractive ante- rior chamber implant in the eye. A method of preparing such a minus power anterior chamber ocular implant comprises first ex- posing an uncoated implant to a plasma to generate a plasma-treated implant having a surface containing amines, carboxylic ac- ids, active free radicals or passive free radicals; and thereafter bonding the medicament to the plasma-treated implant surface. A method of treating myopia comprises surgically implanting and anchoring the implant in the phakic eye to compensate for refrac- tive errors.

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