Thioformamide derivative

Details Thioformamide derivative Thioformamide derivative

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/33 (2006.01) C07D 207/30 (2006.01) C07D 231/10 (2006.01) C07D 233/92 (2006.01) C07D 233/95 (2006.01) C07D 249/02 (2006.01) C07D 263/30 (2006.01) C07D 307/34 (2006.01) C07D 333/04 (2006.01) C07D 487/04 (2006.01) C07D 498/04 (2006.01) C07D 513/04 (2006.01)

Patent

CA 2119876

ABSTRACT A thioformamide derivative represented by the general formula (I), Image (I) which is highly safe, readily available, and useful as an excellent hypotensive and a remedy for cardiac diseases, or a pharmacologically acceptable salt thereof, and a pharmaceutical composition containing the same as the active ingredient wherein Y represents Image , Image , Image , Image , etc. (wherein R7 represents benzyloxy, etc.; R11 and R12 each represent hydrogen, hydroxy, benzoyloxy, benzyloxy, Image (wherein R14 and R15 each represent hydrogen, benzyl, etc.) etc.); Z represents -CH2-, etc.; A represents imidazolyl or imidazopyridyl each of which may have one or two substituents, etc.; R1 and R2 each represent hydrogen, lower alkyl, etc.; and R3 and R4 each represent hydrogen, lower alkyl, etc. - 133 -

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