Solid phase immobilization of phospholipids and cofactor...

G - Physics – 01 – N

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Details

G01N 33/564 (2006.01) C07K 17/00 (2006.01) C07K 14/775 (2006.01) C12N 9/74 (2006.01) C12N 11/00 (2006.01)

Patent

CA 2603814

The present invention provides methods and reagents for detecting antibodies against phospholipid-cofactor proteins. Phospholipids include cardiolipin. Cofactor proteins include beta-2-glycoprotein-1 (i.e., apolipoprotein H) or a prothrombin protein. Detection is accomplished with flow cytometry (e.g., fluorescence-activated cell sorting, facs).

L'invention concerne des méthodes et des réactifs permettant de détecter des anticorps dirigés contre des phospholipides et une protéine-cofacteur.

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