Polymorphic forms of...

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C - Chemistry, Metallurgy

07

D

C07D 401/06 (2006.01) A61K 31/4439 (2006.01) A61P 31/00 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2586177

The present invention relates to novel polymorphic forms of 6-[2~ (methylcarbamoyl)phenylsulfanyl]-3-E-[2-(pyridin-2-yl)ethenyl]indazole, and to processes for their preparation. Such polymorphic forms may be a component of a pharmaceutical composition and may be used to treat a hyperproliferative disorder or a mammalian disease condition mediated by protein kinase activity.

L'invention porte sur de nouvelles formes polymorphiques du 6-[2-(méthylcarbamoyl)phénylsulfanyl]-3-e-[2-(pyridin-2-yl)éthényl]indazole et sur leur procédé de préparation. Lesdites formes polymorphiques peuvent être l'un des constituants d'une préparation pharmaceutique et servir à traiter chez les mammifères certains troubles hyperprolifératifs ou états morbides médiés par la protéine kinase.

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