Polymer formulations for delivery of bioactive agents

Details Polymer formulations for delivery of bioactive agents Polymer formulations for delivery of bioactive agents

A - Human Necessities

61

K

A61K 9/16 (2006.01) A61K 9/22 (2006.01)

Patent

CA 2677498

Disclosed in the present application are compositions comprising a bioresorbable polymer matrix and a bio active agent, wherein the bioactive agent is dispersed within polymer matrix as a solid. Also provided herein are methods for preparing a bioactive agent formulation, wherein the agent is present in a solid form and, wherein the agent is occluded into a polymeric matrix by polymerization of polymer matrix precursors or by self assembly of the polymer.

La présente demande de brevet concerne des compositions comprenant une matrice polymère biorésorbable et un agent bioactif, l'agent bioactif étant dispersé au sein de la matrice polymère sous la forme de particules solides. Elle concerne également des procédés de préparation d'une formulation à base d'un agent bioactif, dans laquelle l'agent est présent sous forme solide et dans laquelle l'agent est occlu dans une matrice polymère par polymérisation de précurseurs de la matrice polymère ou par auto-assemblage du polymère.

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