C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 233/20 (2006.01) A61K 31/222 (2006.01) A61K 31/23 (2006.01) A61K 31/265 (2006.01) A61K 31/77 (2006.01) A61P 25/04 (2006.01) C07C 233/18 (2006.01)
Patent
CA 2606086
Described here are TRPVl agonist compounds and their methods of synthesis and use. In addition to specifically identified compounds, capsaicin prodrugs, gemini dimers, and mutual prodrugs are also described. Formulations of the TRPVl agonist compounds may be in the form of a liquid, tablets, capsules, gel, cream, emulsion, a patch, or the like. Methods for treating medical conditions using the compounds, compositions, or prodrugs described, are also provided.
L'invention concerne des composés agonistes de TRPV1 et leurs méthodes de synthèse et d'utilisation. L'invention concerne également des composés spécifiquement identifiés, des promédicaments de capsicine, des dimères jumeaux et des promédicaments mutuels. L'invention concerne également des formulations de composés agonistes de TRPV1 pouvant se présenter sous la forme d'un liquide, de comprimés, de capsules, de gel, de crème, d'émulsion, de tampon ou analogues. L'invention concerne encore des méthodes pour traiter des troubles médicaux à l'aide des composés, des compositions ou des promédicaments susmentionnés.
Bley Keith R.
Jamieson Gene C.
Muhammad Naweed
Borden Ladner Gervais Llp
Neurogesx Inc.
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