Use of indolamine derivatives for detecting micro-organism...

Details Use of indolamine derivatives for detecting micro-organism... Use of indolamine derivatives for detecting micro-organism...

C - Chemistry, Metallurgy

12

Q

C12Q 1/04 (2006.01) C12Q 1/37 (2006.01)

Patent

CA 2318461

The invention concerns compounds of formula X-NH-R wherein X represents an indole-3-yl group optionally substituted and R represents in particular an acyl residue of an amino acid or of a peptide, enabling to detect a peptidase activity in a micro-organism culture medium, including in a gelled medium, by forming a stain or fluorescence in said medium. The invention is particularly useful for detecting micro-organisms.

Des composés de formule X-NH-R dans laquelle X représente un groupe indole-3- yle éventuellement substitué et R représente notamment le reste acyle d'un acide aminé ou d'un peptide, permettent de détecter une activité de peptidase dans un milieu de culture de micro-organismes, y compris en milieu gélifié, par formation d'une coloration ou d'une fluorescence dans ledit milieu. Application notamment à la détection de micro-organismes.

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