C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 231/12 (2006.01) C07C 231/22 (2006.01) C07C 237/46 (2006.01)
Patent
CA 2710422
This invention relates to the synthesis of iodixanol (1,3-bis(acetamido)-N,N'- bis[3,5-bis(2,3- dihydroxypropylaminocarbonyl)-2,4,6-triiodophenyl]-2-hydroxypropane), more specifically to the dimerisation of 5-acetamido-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo- isophthalamide with a solvent mixture comprising 1-methoxy-2-propanol and water or methanol.
Fetherstonhaugh & Co.
Ge Healthcare As
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