Stress protein-peptide complexes as prophylactic and...

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/00 (2006.01) A61K 38/19 (2006.01) A61K 39/385 (2006.01) A61K 47/48 (2006.01) C07K 17/02 (2006.01)

Patent

CA 2185651

Disclosed is a family of vaccines that contain stress protein-peptide complexes which when administered to a mammal are operative to initiate in the mammal a cytotoxic T cell response against cells infected with a preselected intracellular pathogen. Also disclosed are methodologies for preparing and administering vaccines containing such stress protein-peptide complexes.

L'invention concerne une famille de vaccins qui contient des complexes protéines de stress-peptides. Lorsqu'ils sont administrés à un mammifère ces complexes induisent une réponse des lymphocytes T cytotoxique contre les cellules infectées par un agent pathogène intracellulaires présélectionné. L'invention concerne également des méthodologies pour la préparation et l'administration de vaccins contenant lesdits complexes protéines de stress-peptides.

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