Oral low dose butyrate compositions

Details Oral low dose butyrate compositions Oral low dose butyrate compositions

A - Human Necessities

01

N

A01N 37/10 (2006.01) A01N 25/00 (2006.01) A01N 37/18 (2006.01) A61K 31/165 (2006.01) A61K 31/215 (2006.01) A61K 31/216 (2006.01) A61K 31/22 (2006.01) A61K 31/222 (2006.01) A61K 31/235 (2006.01) A61K 31/25 (2006.01) A61K 45/06 (2006.01) A61K 47/00 (2006.01)

Patent

CA 2366650

This invention relates to orally available compositions which deliver an amount of butyrate or a butyrate analogue effective to ameliorate .beta.- hemoglobinopathies, such as .beta.-thalassemia and sickle cell anemia, cystic fibrosis, cancer and other diseases which are known to be treatable with butyrate. The invention also relates to methods of treating these diseases with such low dose oral compositions.

L'invention concerne des compositions orales apportant une certaine dose de butyrate ou d'un analogue de butyrate, et qui sont efficaces pour améliorer les .beta. hémoglobinopathies, telles que la .beta. thalassémie, la drépanocytose, la fibrose kystique, le cancer, et d'autres maladies connues pour pouvoir être traitées à l'aide du butyrate. L'invention concerne également des méthodes de traitement de ces maladies à l'aide de telles compositions orales faiblement dosées.

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