A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/14 (2006.01)
Patent
CA 2601969
There is provided pharmaceutical compositions in the form of homogeneous interactive mixtures, which compositions comprise a pharmacologically- effective amount of an active ingredient in the form of microparticles of a size between about 0.5 ~m and about 10 ~m, which particles are attached to the surfaces of larger carrier particles with a size range of between about 10 and about 100 ~m. The carrier particle material is preferably bio- and/or mucoadhesive in its nature.
La présente invention se rapporte à des compositions pharmaceutiques se présentant sous la forme de mélanges interactifs homogènes. Les compositions pharmaceutiques selon l'invention contiennent une quantité pharmacologiquement efficace d'un ingrédient actif sous forme de microparticules présentant une taille comprise entre environ 0,5 et environ 10 ?m, lesdites particules étant liées à la surface de particules porteuses plus grandes, dont la taille est comprise entre environ 10 et environ 100 ?m. La matière constituant les particules porteuses est de préférence de nature bioadhésive et/ou mucoadhésive.
Bjoerk Erik
Fransen Nelly
Nystroem Christer
Borden Ladner Gervais Llp
Orexo Ab
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