C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/06 (2006.01) C07D 207/327 (2006.01) C07D 209/04 (2006.01) C07D 209/44 (2006.01) C07D 213/48 (2006.01) C07D 213/55 (2006.01) C07D 215/14 (2006.01) C07D 241/12 (2006.01) C07D 307/38 (2006.01) C07H 21/00 (2006.01) C07K 1/04 (2006.01)
Patent
CA 2195089
This invention features methods of synthesizing combinatorial libraries of chemical compounds, and combinatorial libraries of chemical compounds formed by the methods of this invention. Specifically, Diels-Alder chemistry is utilized to generate libraries of diverse molecules which are easily differentially functionalized with various chemical moities and in one aspect are configured to act as non-hydrolyzable peptidomimetics.
La présente invention concerne, d'une part des procédés de synthèse de bibliothèques combinatoires de composés chimiques, et d'autre part des bibliothèques combinatoires constituées selon les procédés de la présente invention. En l'occurrence, on a eu recours à la chimie de Diels-Alder pour générer des bibliothèques de diverses molécules facilement fonctionnalisables de façon différentielle grâce à différentes fractions chimiques et qui sont configurées pour se comporter comme des peptidomimétiques non hydrolysables.
Smart & Biggar
The Scripps Research Institute
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