Piperazine with or-substituted phenyl group and their use as...

Details Piperazine with or-substituted phenyl group and their use as... Piperazine with or-substituted phenyl group and their use as...

C - Chemistry, Metallurgy

07

D

C07D 295/192 (2006.01) A61K 31/495 (2006.01) A61K 31/497 (2006.01) A61P 25/28 (2006.01) C07D 213/74 (2006.01)

Patent

CA 2534675

The invention relates to compounds of formula (I) wherein the substituents are described in claim 1. The compounds may be used in the treatment of illnesses based on the glycine uptake inhibitor, such as psychoses, pain, neurodegenerative disfunction in memory and learning, schizophrenia, dementia and other diseases in which cognitive processes are impaired, such as attention deficit disorders or Alzheimer's disease.

L'invention concerne des composés de la formule (I), dans laquelle les substituants sont tels que décrits dans la revendication 1. Les composés peuvent être utilisés dans le traitement de maladies sur la base de l'inhibiteur de la capture du glycocolle, telles que psychoses, douleurs, dysfonctionnement neurodégénératif de la mémoire et de l'acquisition de connaissances, schizophrénie, démence et d'autres états pathologiques dans lesquels les processus cognitifs présentent des défaillances, notamment des troubles marqués par une déficience de l'attention ou la maladie d'Alzheimer.

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