Generation of antibodies using polynucleotide vaccination in...

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 16/00 (2006.01) A61K 48/00 (2006.01) C07K 14/02 (2006.01) C07K 14/705 (2006.01) C07K 16/02 (2006.01) C12N 9/12 (2006.01) C12N 15/70 (2006.01) C12N 15/85 (2006.01) C12N 15/867 (2006.01) C12Q 1/68 (2006.01) G01N 33/577 (2006.01)

Patent

CA 2350111

The present invention relates to a process for producing antibodies to an antigen in an avian species using polynucleotide vaccination. The present invention also relates to a process for determining the proteomics profile of a set of pre-selected DNA sequences isolated from a bio-sample, preferably the proteomics profile of a human cDNA library. The present invention further relates to a process for identifying physiologically distinguishable markers associated with a physiologically abnormal bio-sample.

La présente invention concerne la production, dans le cas d'une espèce aviaire, d'anticorps dirigés contre un antigène par vaccination polynucléotidique. L'invention concerne également la détermination du profil protéomique d'un jeu de séquences d'ADN préalablement sélectionnées et isolées à partir d'un échantillon biologique, et plus particulièrement la détermination du profil protéomique d'une échantillothèque d'ADN complémentaire d'origine humaine. L'invention concerne en outre l'identification de marqueurs physiologiquement distinguables associés à un échantillon biologique physiologiquement anormal.

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