Methods and reagents for isolating biologically active peptides

Details Methods and reagents for isolating biologically active peptides Methods and reagents for isolating biologically active peptides

C - Chemistry, Metallurgy

12

N

C12N 15/10 (2006.01) C12N 5/10 (2006.01) C12N 15/62 (2006.01) C12N 15/63 (2006.01)

Patent

CA 2346500

One aspect of the present invention is the synthesis of a binary method that combines variegated peptide display libraries, e.g., in a "display mode", with soluble secreted peptide libraries, e.g., in a "secretion mode", to yield a method for the efficient isolation of peptides having a desired biological activity.

Cette invention concerne notamment la combinaison de deux méthodes concernant l'une des banques de peptides panachés, dits en <= mode d'affichage >=, l'autre des banques de peptides en sécrétion soluble, dit en <= mode sécrétion >=, dont la synthèse donne le jour à un procédé qui permet d'isoler efficacement des peptides caractérisés par une activité biologique d'intérêt.

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