A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/155 (2006.01) A61K 9/22 (2006.01) A61K 9/32 (2006.01) A61P 1/10 (2006.01)
Patent
CA 2599531
The present invention is directed to methods and formulations for treating chronic constipation. The methods and formulations include, but are not limited to, methods and formulations for delivering effective concentrations of metformin for treating chronic constipation and further comprise at least one pharmaceutically acceptable ingredient to control the release of the metformin, wherein following administration, the release of metformin is distal to the gastrointestinal sites to achieve systemic absorption of metformin. The invention is also directed to treating constipation as a symptom associated with other diseases and conditions such as irritable bowel syndrome.
La présente invention concerne des méthodes et des préparations destinées à traiter la constipation chronique. Ces méthodes et ces préparations incluent, entre autres, des méthodes et des préparations destinées à l'administration de doses efficaces de metformine pour le traitement de la constipation chronique, et comprennent en outre au moins un ingrédient pharmaceutiquement acceptable destiné à réguler la libération de la metformine. Après administration, la libération de metformine est distale par rapport aux sites gastro-intestinaux, ce qui permet d'obtenir une absorption systémique de la metformine. L'invention concerne également le traitement de la constipation en tant que symptôme associé à d'autres maladies et affections, telles que le syndrome du côlon irritable.
Agi Therapeutics Research Ltd.
Kirby Eades Gale Baker
LandOfFree
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