Imidazolidine-2,4-dione derivatives and use thereof as a...

Details Imidazolidine-2,4-dione derivatives and use thereof as a... Imidazolidine-2,4-dione derivatives and use thereof as a...

C - Chemistry, Metallurgy

07

D

C07D 403/06 (2006.01) A61K 31/4166 (2006.01) A61P 35/00 (2006.01) C07D 403/12 (2006.01)

Patent

CA 2758638

The subject matter of the present application is novel imidazolidine-2,4-dione derivatives of general formula (I) in which R1, R2, R3 and X are variables. These products have an anti-proliferative activity. They are particularly advantageous for treating pathological conditions and diseases associated with abnormal cell proliferation, such as cancers. The invention also relates to pharmaceutical compositions containing said products and to the use thereof for preparing a medicament.

La présente demande a pour objet de nouveaux dérivés d'imidazolidine-2,4-dione de formule générale (I) dans laquelle R1, R2, R3 et X sont des variables. Ces produits ont une activité anti- proliférative. Ils sont particulièrement intéressants pour traiter les états pathologiques et les maladies liés à une prolifération cellulaire anormale tels que les cancers. L'invention concerne également des compositions pharmaceutiques contenant lesdits produits et leur utilisation pour la préparation d'un médicament.

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