Non nucleoside reverse transcriptase inhibitors

C - Chemistry – Metallurgy – 07 – F

Patent

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Details

C07F 9/38 (2006.01) A61K 31/4155 (2006.01) A61P 31/18 (2006.01) C07D 243/04 (2006.01) C07D 403/06 (2006.01) C07F 9/40 (2006.01) C07F 9/62 (2006.01) C07F 9/645 (2006.01) C07F 9/653 (2006.01) C07F 9/655 (2006.01) C07F 9/6558 (2006.01) C07F 9/6561 (2006.01) C12N 9/16 (2006.01) C12Q 1/44 (2006.01)

Patent

CA 2481285

Phosphorus-substituted imidazole compounds with anti-HIV properties having use as therapeutics and for other industrial purposes are disclosed. The compositions inhibit reverse transcriptase activity and are useful therapeutically for the inhibition of such enzymes, as well as in assays for the detection of such enzymes.

L'invention concerne des composés d'imidazole à substitution phosphore présentant des propriétés anti-VIH, utiles en tant qu'agents thérapeutiques et pour d'autres applications industrielles. Ces compositions inhibent l'activité transcriptase inverse et présentent une efficacité thérapeutiques pour l'inhibition de ces enzymes, ainsi que pour la détection de ces enzymes dans des épreuves biologiques.

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