Tetrahydroisoquinoline derivatives as lhrh antagonists

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 217/04 (2006.01) A61K 31/472 (2006.01) A61P 5/00 (2006.01) C07D 217/14 (2006.01) C07D 217/16 (2006.01) C07D 217/18 (2006.01) C07D 217/20 (2006.01) C07D 217/22 (2006.01) C07D 217/26 (2006.01) C07D 221/00 (2006.01) C07D 223/16 (2006.01) C07D 317/00 (2006.01) C07D 319/00 (2006.01) C07D 401/06 (2006.01) C07D 401/08 (2006.01) C07D 401/10 (2006.01) C07D 401/12 (2006.01) C07D 491/04 (2006.01)

Patent

CA 2351187

Tetrahydroisoquinoline derivatives of formula (I): or a pharmaceutically acceptable salt, ester, or prodrug thereof, having activity as an LHRH antagonist, as well as pharmaceutical compositions containing the same, and methods for their use and preparation.

L'invention concerne des dérivés de tétrahydro-isoquinoléine de formule (I), ou un sel, un ester pharmaceutiquement acceptables, ou un promédicament de ces derniers, possédant une activité d'antagoniste LHRH, ainsi que des compositions pharmaceutiques les contenant, et des procédés de leur utilisation et préparation.

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