Oxazinocarbazoles for the treatment of cns diseases

Details Oxazinocarbazoles for the treatment of cns diseases Oxazinocarbazoles for the treatment of cns diseases

C - Chemistry, Metallurgy

07

D

C07D 498/06 (2006.01) A61K 31/5383 (2006.01) A61P 25/18 (2006.01) A61P 25/24 (2006.01) C07D 209/00 (2006.01) C07D 265/00 (2006.01)

Patent

CA 2376927

The present invention provides oxazinocarbazole derivatives having a ring connecting position 8 (C-8) and position 9 (N-9), and more specifically, provides compounds of formula (I) wherein R1, R2, R3 and R4 are described herein. These compounds are 5-HT ligands, and are useful for treating diseases wherein modulation of 5-HT activity is desired.

La présente invention concerne des dérivés d'oxazinocarbazoles qui possèdent un cycle reliant la position 8 (C-8) et la position 9 (N-9), et plus particulièrement cette invention concerne des composés représentés par la formule (I). Dans cette formule R¿1?, R¿2?, R¿3? et R¿4? sont décrits dans les spécifications. Ces composés sont des ligands 5-HT, et conviennent pour le traitement de maladies dans lesquelles la modulation de l'activité 5-HT est recherchée.

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