Vectors for ocular transduction and use thereof for genetic...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/861 (2006.01) A61K 48/00 (2006.01) A61P 27/02 (2006.01) C12N 5/10 (2006.01)

Patent

CA 2407881

Adenovirus vector-based gene therapy methods for treating ocular disorders are provided. Adenovirus vectors for therapy of ocular diseases and methods of treatment using the vectors are provided. Compositions, kits, and methods of preparation and use of the vectors for gene therapy are provided.

Cette invention concerne des méthodes de thérapie génique à base de vecteurs adénoviraux pour le traitement de troubles oculaires. L'invention concerne également des vecteurs adénoviraux pour la thérapie de pathologies de l'oeil et des méthodes de traitement faisant intervenir ces vecteurs. De plus, l'invention porte sur des compositions, des trousses et des méthodes de préparation et d'utilisation desdits vecteurs pour thérapie génique.

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