Insulin analogs

Details Insulin analogs Insulin analogs

C - Chemistry, Metallurgy

07

K

C07K 14/62 (2006.01) A61K 38/28 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2151134

Analogs of human insulin containing an Ala, Gly, Val, Leu, Ile and Pro residue at position 26 of the B chain, and optionally, having modifications at other positions, display modified physico-chemical and pharmacokinetic properties. These analogs are useful in the treatment of hyperglycemia because they are stable and display a low tendency to self-aggregate.

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