Method and composition for treatment of ocular hypertension...

A - Human Necessities – 61 – K

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A61K 31/557 (2006.01) A61K 31/5575 (2006.01)

Patent

CA 2458230

Provided is a method for treating ocular hypertension and glaucoma, which comprises administrating an effective amount of 15-keto-prostaglandin compound having a ring structure at the end of the .omega. chain to the eyes of a mammalian subject in need of such treatment once a day. According to the method, single administration of the compound effectively lower the IOP of the subject throughout the day.

Procédé de traitement de l'hypertension oculaire et du glaucome qui consiste à administrer une quantité efficace du composé 15-céto-prostaglandine ayant une structure annulaire à l'extrémité de la chaîne .omega. dans les yeux d'un sujet mammalien nécessitant ce traitement une fois par jour. Selon ce procédé, une seule administration de ce composé permet de réduire efficacement la tension oculaire du sujet durant toute une journée.

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