Oral immediate release formulation of a poorly water-soluble...

A - Human Necessities – 61 – K

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Details

A61K 31/55 (2006.01) A61K 47/02 (2006.01) A61K 47/26 (2006.01) A61K 47/34 (2006.01)

Patent

CA 2590848

The invention is related to an oral immediate release formulation of Benzazepin -1- acetic acid derivatives comprising: a) said active substance in an amount of up to 65% of the total weight of the formulation; b) at least 10% w/w an alkaline compound or a mixture of alkaline compounds; c) between 0.1 and 10% of one or more surfactants, and d) optionally comprises auxiliary materials an amount of between 1% and 45% of the total weight of the formulation.

La présente invention a trait à une formulation orale de dérivés de l'acide benzazépine-1- acétique à libération instantanée comportant: a) ladite substance active en une quantité allant jusqu'à 65 % du poids total de la formulation; b) au moins 10 % en poids d'un composé alcalin ou d'un mélange de composés alcalins; c) entre 0,1 et 10 % d'un ou de plusieurs tensioactifs, et d) éventuellement comportant des substances auxiliaires en une quantité comprise entre 1 % et 45 % du poids total de la formulation.

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