Autologous self-tolerance inducing cells of monocytic origin...

A - Human Necessities – 61 – K

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A61K 35/14 (2006.01) C12N 5/0783 (2010.01) C12N 5/0786 (2010.01) A61P 37/06 (2006.01) A61P 37/08 (2006.01)

Patent

CA 2531627

The invention relates to cells of monocytic origin suitable for the prevention and/or treatment of diseases associated with disturbed self-tolerance, in particular autoimmune diseases and allergies, and to pharmaceutical preparations containing these cells. The cells are autologous in relation to the patient to whom they are to be administered. The invention further relates to a process for the generation and/or, propagation of autologous regulatory T cells.

L'invention concerne des cellules d'origine monocytique appropriées pour prévenir et/ou traiter des maladies associées à une perturbation de l'autotolérance, en particulier, des maladies auto-immunes et des allergies; et les préparations pharmaceutiques contenant ces cellules. Lesdites cellules sont autologues par rapport au patient auquel elles doivent être administrées. L'invention concerne également une méthode permettant de produire et/ou propager des lymphocytes T autologues régulateurs.

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