Perfluoroalkyl-containing complexes comprising sugar...

Details Perfluoroalkyl-containing complexes comprising sugar... Perfluoroalkyl-containing complexes comprising sugar...

C - Chemistry, Metallurgy

07

H

C07H 15/26 (2006.01) A61K 31/7028 (2006.01) A61K 31/7052 (2006.01) A61K 49/00 (2006.01) C07D 405/14 (2006.01) C07H 15/04 (2006.01) C07H 23/00 (2006.01) C07D 257/02 (2006.01)

Patent

CA 2418790

The invention relates to perfluoroalkyl-containing complexes comprising sugar residues of the general formula (I), wherein R represents a mono- or oligosaccharide residue bound in the 1-OH or 1-SH position, Rf represents a perfluorated carbon chain, K is a metal complex and Y and Z are linker groups. The inventive complexes are suitable for use in intravenous lymphography, in tumor diagnosis and for infarct and necrosis imaging.

L'invention concerne des complexes perfluoroalkylés renfermant des résidus saccharides, de formule générale (I), dans laquelle R désigne un résidu mono- ou oligosaccharide lié en position 1-OH ou 1-SH, R¿f? désigne une chaîne carbonée perfluorée, K désigne un complexe métallique, et Y et Z désignent des groupes de liaison. Ces complexes conviennent pour l'utilisation en lymphographie intraveineuse, dans le diagnostic des tumeurs et en imagerie d'infarctus et de nécroses.

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