C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 413/14 (2006.01)
Patent
CA 2719515
The present invention relates to a novel benzoxazine benzimidazole derivative of formula (1) as an antagonist against a vanilloid receptor-1, a pharmaceutical composition comprising the same as an active ingredient, and a use thereof. The benzoxazine benzimidazole derivative of the present invention may be useful for preventing or treating a disease associated with antagonistic activity of vanilloid receptor-1: (see formula I) wherein, R1, R2, R3, R3', Q1, Q2, Q3 and Q4 have same meanings as defined in the specification.
La présente invention concerne un antagoniste du récepteur vanilloïde de type 1, qui est un nouveau dérivé de benzoxazine benzimidazole, ainsi qu'une composition pharmaceutique le comprenant et une application s'y rapportant. Le dérivé de benzoxazine benzimidazole selon la présente invention peut être bénéfiquement utilisé dans la prévention et le traitement d'états médicaux associés à l'activité antagoniste du récepteur vanilloïde.
Cho Min Jae
Cho Seong Hee
Hyun Hyae Jung
Kim Inwoo
Kim Ji Duck
Daewoong Pharmaceutical Co. Ltd.
Ridout & Maybee Llp
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