Stable preparation of water-soluble salts of...

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A61K 31/565 (2006.01) A61K 47/02 (2006.01) A61K 47/10 (2006.01) A61K 47/12 (2006.01) A61K 47/18 (2006.01) A61K 47/36 (2006.01)

Patent

CA 1047404

Abstract of the Disclosure A water-soluble salt of dehydroepiandrosterone sulfate is dissolved in an aqueous solution of a compound selected from the group consisting of dextran, macrogol, a neutral amino acid, a basic amino acid, an alkali metal salt of a weak acid, a solid amine, and mixtures thereof and then the resulting mixture is lyophilized. The product is stable on storage for a long period of time and easily soluble in water upon use for parenteral administration.

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