Random chemistry for the generation of new compounds

C - Chemistry – Metallurgy – 12 – P

Patent

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C12P 1/00 (2006.01) C07B 61/00 (2006.01) C07H 21/00 (2006.01) C07K 1/00 (2006.01) C07K 1/04 (2006.01) C12N 9/00 (2006.01) C12N 15/10 (2006.01) C12P 19/34 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2160457

Methods for the generation of new compounds are disclosed. The present invention eliminates the need to know in advance the structure or chemical compounds of a compounds having a desired property. The disclosure of the present invention provides that diversity of unknown compounds may be produced by "random" chemistry, and such a diversity of unknown compounds may be screened for one or more desired properties to detect the presence of suitable compounds. In one aspect, a starting group of organic compounds is caused to undergo a series of chemical reactions to create a diversity of new organic compounds that are screened for the presence of organic compounds having the desired property. In another aspect of the present invention, a diversity of compounds is generated from a group of substrates which are subjected to a group of enzymes representing a diversity of catalytic activities.

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