G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/577 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) C07K 14/75 (2006.01) C07K 16/18 (2006.01) C07K 16/36 (2006.01) G01N 33/53 (2006.01) G01N 33/566 (2006.01) G01N 33/573 (2006.01) G01N 33/86 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2166386
The subject invention relates a method for the production of monoclonal antibodies. The method utilizes an immunized germfree animal. The invention also provides methods for the use of such monoclonal antibodies, and polyclonal antibodies derived from an immunized germfree animal, for in vitro and in vivo clinical diagnostics and therapeutics. Also, the subject invention provides a fibrin- specific monoclonal antibody.
La présente invention concerne une méthode pour la production d'anticorps monoclonaux. On utilise un animal axénique immunisé. L'invention concerne également des méthodes d'utilisation de tels anticorps monoclonaux, ainsi que des anticorps polyclonaux dérivés d'un animal axénique immunisé, pour des diagnostics cliniques effectués in vivo et in vitro et à des fins thérapeutiques. La présente invention concerne également un anticorps monoclonal spécifique de la fibrine.
Gargan Paul E.
Pleasants Julian R.
Ploplis Victoria A.
American Biogenetic Sciences Inc.
Osler Hoskin & Harcourt Llp
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