A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/107 (2006.01) A61K 38/12 (2006.01) A61K 38/28 (2006.01) A61K 38/55 (2006.01) A61K 47/20 (2006.01)
Patent
CA 2410065
Pharmaceutical compositions comprising a macromolecular pharmaceutical agent in mixed micellar form are disclosed. The mixed micelles are formed from an alkali metal alkyl sulfate, and at least three different micelle-forming compounds as described in the specification. Micelle size ranges between about 1 and 10 nanometers. Methods for making and using the compositions are also disclosed. A preferred method for administering the present composition is through the buccal region of the mouth.
L'invention concerne des compositions pharmaceutiques comprenant un agent pharmaceutique macromoléculaire sous forme micellaire mélangée. Les micelles mélangées sont formées à partir d'un sulfate d'alkyle de métal alcalin, ainsi que d'au moins trois composés différents formant des micelles telles que décrites dans la description. La taille des micelles est comprise entre environ 1 et 10 nanomètres. L'invention concerne également des procédés de préparation et d'utilisation des compositions. Un procédé préféré d'administration de la présente composition consiste en une administration par la région buccale de la bouche.
Generex Pharmaceuticals Inc.
Perry + Currier
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