Novel enantiomerically pure beta-agonists, method for the...

C - Chemistry – Metallurgy – 07 – D

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C07D 265/36 (2006.01) A61K 31/538 (2006.01) A61P 11/00 (2006.01) C07D 413/04 (2006.01)

Patent

CA 2562859

The invention relates to enantiomerically pure compounds of formula (1), wherein the radicals R1, R2, R3, R4 and X are defined as in claims and a description. A method for producing said compounds and the use thereof in the form of a drug, in particular as a drug for treating respiratory tract diseases are also disclosed. The synthesis of the compounds is carried out by means of a chiral epoxide of formula (5).

La présente invention concerne des composés énantiomériquement purs correspondant à la formule générale (1), dans laquelle R?1¿, R?2¿, R?3¿, R?4¿ et X?-¿ peuvent correspondre à la définition donnée dans les revendications et dans la description. L'invention concerne également un procédé de production de ces composés et leur utilisation comme médicament, en particulier comme médicament pour le traitement de maladies des voies respiratoires. La synthèse de ces composés se fait par l'intermédiaire d'époxydes chiraux correspondant à la formule (5).

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