Substituted 3,3-diamino-2-propenenitriles, their preparation...

C - Chemistry – Metallurgy – 07 – C

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C07C 255/06 (2006.01) A61K 31/275 (2006.01) A61K 31/33 (2006.01) C07C 253/30 (2006.01) C07C 255/30 (2006.01) C07C 255/58 (2006.01) C07C 317/48 (2006.01) C07D 207/26 (2006.01) C07D 211/00 (2006.01) C07D 211/42 (2006.01) C07D 211/58 (2006.01) C07D 213/00 (2006.01) C07D 213/38 (2006.01) C07D 213/40 (2006.01) C07D 213/74 (2006.01) C07D 213/75 (2006.01) C07D 217/00 (2006.01) C07D 217/04 (2006.01) C07D 217/06 (2006.01) C07D 223/10 (2006.01) C07D 233/00 (2006.01) C07D 239/42 (2006.01) C07D 295/00 (2006.01) C07D 29

Patent

CA 2289099

Substituted cyanoenamines of general formula (I) wherein Z, R1, R2 and R3 are defined in the description, compositions thereof and methods for preparing the compounds are described. The compounds are useful in the treatment of diseases of the central nervous system, the cardiovascular system, the pulmonary system, the gastrointestinal system and the endocrinological system.

L'invention concerne des cyanoénamines selon la formule générale (I). Dans cette dernière, Z, R?1¿, R?2¿ et R?3¿ sont tels que définis dans le descriptif. L'invention traite également de compositions de ces derniers et de procédés de préparation de ces composés. Ces composés permettent de traiter des maladies du système nerveux central, du système cardiovasculaire, du système pulmonaire, du système gastro-intestinal et du système endocrinonien.

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