A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/145 (2006.01)
Patent
CA 2601022
The present invention relates to influenza vaccine formulations and vaccination regimes for immunising against influenza disease. In particular the invention relates to vaccine formulations comprising an oil-in-water emulsion adjuvant and optionally 3D-MPL, their use in medicine, in particular their use in augmenting immune responses to influenza antigens, and to methods of preparation, wherein the oil in water emulsion comprises a sterol, a metabolisable oil and an emulsifying agent.
La présente invention concerne des formulations de vaccin contre la grippe et des régimes de vaccination pour l~immunisation contre la maladie de la grippe. L~invention concerne en particulier des formulations de vaccin comprenant un adjuvant de type émulsion huile dans l~eau et de façon facultative le 3D-MPL, leur utilisation en médecine, en particulier leur utilisation dans l~augmentation des réponses immunes aux antigènes de la grippe, et des procédés de préparation. L~émulsion huile dans l~eau comprend un stérol, une huile métabolisable et un agent émulsifiant.
Hanon Emmanuel Jules
Stephenne Jean
Glaxosmithkline Biologicals S.a.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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