Process for preparing crystalline ciclesonide with defined...

Details Process for preparing crystalline ciclesonide with defined... Process for preparing crystalline ciclesonide with defined...

C - Chemistry, Metallurgy

07

J

C07J 71/00 (2006.01) B01F 1/00 (2006.01) C07J 75/00 (2006.01)

Patent

CA 2519752

The invention relates to a novel process for preparing crystalline ciclesonide with an advantageous particle size and to the use for producing pharmaceutical preparations, in particular for topical use. The crystalline ciclesonide obtained by the novel process has advantageous aerodynamic properties, and can be further processed to inhalable or nasally administered pharmaceutical preparations without further mechanical micronization.

L'invention concerne un nouveau procédé de préparation de ciclésonide cristallin dotée d'une granulométrie avantageuse, ainsi que son utilisation pour la production de préparations pharmaceutiques, en particulier, pour l'usage topique. Le ciclénoside cristallin obtenu par ce nouveau procédé présente des propriétés aérodynamiques avantageuses et peut, en outre, être traité pour des préparations pharmaceutiques inhalables ou administrées par voies nasales sans autre micronisation.

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