Carrier immunoglobulins and uses thereof

Details Carrier immunoglobulins and uses thereof Carrier immunoglobulins and uses thereof

C - Chemistry, Metallurgy

07

K

C07K 16/00 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) C07K 16/46 (2006.01) C07K 19/00 (2006.01) C12N 15/13 (2006.01)

Patent

CA 2755336

Disclosed is an isolated antigen binding protein, such as but not limited to, an antibody or antibody fragment. Also disclosed are pharmaceutical compositions and medicaments comprising the antigen binding protein, isolated nucleic acid encod-ing it, vectors, host cells, and hybridomas useful in methods of making it. In some embodiments the antigen binding protein com-prises one to twenty-four pharmacologically active chemical moieties conjugated thereto, such as a pharmacologically active polypeptide.

La présente invention concerne une protéine de liaison d'antigène isolée, telle que, mais non limitée à, un anticorps ou fragment d'anticorps. La présente invention concerne en outre des compositions pharmaceutiques et des médicaments comprenant la protéine de liaison d'antigène, un acide nucléique isolé codant pour celui-ci, des vecteurs, des cellules hôtes, et des hybridomes utiles dans des procédés de préparation de celle-ci. Dans certains modes de réalisation, la protéine de liaison d'antigène comprend un à vingt-quatre fragments chimiques pharmacologiquement actifs conjugués à celle-ci, tels qu'un polypeptide pharmacologiquement actif.

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