Compositions and treatments for pneumonia in animals

Details Compositions and treatments for pneumonia in animals Compositions and treatments for pneumonia in animals

C - Chemistry, Metallurgy

12

N

530/13, 167/135,

C12N 15/31 (2006.01) A61K 39/102 (2006.01) A61K 39/40 (2006.01) C07K 7/04 (2006.01) C07K 14/285 (2006.01) C12N 1/00 (2006.01) C12P 21/02 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2014033

Abstract New proteins and subunit antigens from P. haemolytica for use in stimulating immunity against respiratory diseases such as pneumonia, including shipping fever pneumonia, are disclosed. The subunit antigens include immunogenic amino acid sequences of P. haemolytica fimbrial protein, P. haemolytica plasmin receptor protein, and P. haemolytica 50K outer membrane protein and P. haemolytica leukotoxin. The antigens can be used in a vaccine composition, either alone or in combination. Also disclosed are methods of vaccination as well as methods of making the subunit antigens employed in the vaccines.

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