Methods and compositions for the detection of protein...

G - Physics – 01 – N

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G01N 33/68 (2006.01) G01N 33/53 (2006.01) C07K 14/47 (2006.01)

Patent

CA 2662863

A method is provided for the detection of misfolded proteins in a sample. These methods may be used to diagnose or indicate the potential for developing a disease associated with protein aggregation. In particular a method for serial automated cyclic amplification of a misfolded protein is disclosed.

L'invention concerne une méthode de détection de protéines mal repliées dans un échantillon. Lesdites méthodes peuvent être utilisées pour diagnostiquer ou indiquer le risque de développer une maladie associée à une agrégation de protéines. L'invention concerne en particulier une méthode d'amplification en série, cyclique, automatique, d'une protéine mal repliée.

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