Surface protein of staphylococcus aureus

Details Surface protein of staphylococcus aureus Surface protein of staphylococcus aureus

C - Chemistry, Metallurgy

12

N

C12N 15/31 (2006.01) A61K 39/085 (2006.01) C07K 14/31 (2006.01) C07K 16/12 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2192175

Methods and compositions are provided for preventing Staphylococents infections associated with the use of catheters and similar devices. They are based on the neutralization of ability of surface proteins of staphylococcis to adhere to the surface of the catheters at the skin-catheter junction as the first step in the systemic invasion of the host by the organism.

Cette invention se rapporte à des procédés et à des compositions servant à empêcher les infections par le staphylocoque doré qui sont associées à l'utilisation de cathéters et de dispositifs similaires. Ces procédés et ces compositions se fondent sur la neutralisation de la capacité qu'ont des protéines de surface du staphylocoque d'adhérer à la surface des cathéters à l'endroit de la jonction entre la peau et le cathéter, cette adhésion constituant la première étape de l'invasion systémique de l'organisme hôte par le staphylocoque.

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