Monosebacate of pyrazole derivative

Details Monosebacate of pyrazole derivative Monosebacate of pyrazole derivative

C - Chemistry, Metallurgy

07

H

C07H 17/02 (2006.01) A61K 31/7056 (2006.01) A61P 3/00 (2006.01) A61P 3/04 (2006.01) A61P 3/06 (2006.01) A61P 3/08 (2006.01) A61P 3/10 (2006.01) A61P 7/10 (2006.01) A61P 9/04 (2006.01) A61P 9/10 (2006.01) A61P 9/12 (2006.01) A61P 19/06 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2709530

The present invention provides a novel form of 3-(3-{4-[3-(.beta.-D-gluco- pyranosyloxy)-5-isopropyl-1H-pyrazol-4-ylmethyl]-3-methylphenoxy}propylamino)- 2,2-dimethylpropionamide with improved storage stability. Since bis[3-(3-{4-[3- (.beta.-D- glucopyranosyloxy)-5-isopropyl-1H-pyrazol-4-ylmethyl]-3-methylphenoxy}propyl- amino)-2,2-dimethylpropionamide] monosebacate has extremely excellent storage stability, it is useful as a drug substance. Furthermore, it shows an extremely good crystalline property and can be purified by a convenient method, and therefore is suitable for the industrial preparation.

La présente invention concerne une nouvelle forme de 3-(3-{4-[3-(ß-D-glucopyranosyloxy)-5-isopropyl-1H-pyrazol-4-ylméthyl]-3-méthylphénoxy}-propylamino)-2,2-diméthylpropionamide dont la stabilité au stockage est améliorée. Etant donné que le monosébacate de bis[3-(3-{4-[3-(ß-D-glucopyranosyloxy)-5-isopropyl-1H-pyrazol-4-ylméthyl]-3-méthylphénoxy}-propylamino)-2,2-diméthylpropionamide présente une stabilité au stockage des plus excellentes, il est utile comme substance médicamenteuse pharmaceutique. En outre, il présente une excellente propriété de cristallinité et peut être purifié par un procédé simple, et est ainsi adapté à la production industrielle.

Affiliated with

Also associated with

Rating

Monosebacate of pyrazole derivative does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Monosebacate of pyrazole derivative, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Monosebacate of pyrazole derivative will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1947984