Methods and compositions for the assessment of...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01) C07K 16/00 (2006.01) C12N 15/11 (2006.01)

Patent

CA 2629388

The present invention provides methods for the assessment of risk of developing acute coronary syndrome (ACS) in smokers and non-smokers using analysis of genetic polymorphisms. The present invention also relates to the use of genetic polymorphisms in assessing a subject's risk of developing ACS. Nucleotide probes and primers, kits, and microarrays suitable for such assessment are also provided.

La présente invention concerne des méthodes destinées à évaluer le risque de développer un syndrome coronarien aigu (SCA) chez les fumeurs et les non-fumeurs au moyen d'une analyse de polymorphismes génétiques. La présente invention concerne également l'utilisation de polymorphismes génétiques dans l'évaluation du risque que présente un sujet de développer un SCA. L'invention concerne en outre des sondes et des amorces nucléotidiques, des trousses et des microréseaux destinés à cette évaluation.

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